MEDISPA.PRO
Ministry of Health code: A20.30.024.007 Axis M6 · Immunity and systemic inflammation CEBM: Level D (Blood purification and detoxification)

Minor autohaemotherapy (including with ozone)

Minor Autohemotherapy

Industry clinical and economic procedure passport. Full biological mechanism (MoA), patient preparation protocol, first-choice equipment fleet, integration into the resort's master treatment rooms and market price benchmarks.

To the procedure catalogue Equipment fleet Integration treatment rooms Rates and economics
Session duration
20 min
Turnover: ~35 min
Recommended course
8 sessions
8 treatments – an assumption for the economic calculation; the course is prescribed by a physician
Throughput capacity
14 pts
per 8-hour shift
Median rate
2 050 ₽
1 725 ₽ – 2 375 ₽
Course cost
16 400 ₽
at market median
Publication volume
Level D
4 publ. in PubMed

Clinical profile

Intramuscular injection of a small volume of the patient's own venous blood, sometimes mixed with ozone. Few studies specifically on minor autohaemotherapy with ozone are in PubMed so far; there are reviews of intramuscular autologous blood injection in urticaria and eczema with mixed results.

Every statement links to a publication in the list below. This is a snapshot of published research, not a final assessment of the method: international practice and integrated protocols often run ahead of official publications. Draft based on published research; requires review by a physician. Revision: 2026-10-17.

Mechanism of action

  • The mechanisms of action of intramuscular autohaemotherapy have not been studied and require research. [1]

Where studies show an effect

  • Urticaria and atopic eczema: some evidence of effect, no firm conclusions. [1]
  • Acne and COPD: positive results from reviews of studies injecting blood into acupuncture points, with low-quality studies. [3, 4]

Open questions and study limitations

  • In chronic urticaria, differences from placebo did not reach significance in a 2019 meta-analysis. [2]

Safety

  • No significant adverse events were reported in the urticaria meta-analysis. [2]
Contraindications. Contraindications are determined by the physician according to the equipment or drug instructions; they are not given in study abstracts.

Equipment fleet and fit-out

Certified first-choice medical equipment and compatible device systems

Equipment registry
Base configuration (Hero Device)
Medical ozone generator

Device platform with proven validation of the biological response. Includes built-in biofeedback sensor systems, patient protection protocols and precision dosing of exposure.

Certification: Russian Ministry of Health registration certificate / CE Medical Device Directive Class IIa/IIb.
Compatible platforms in the MEDISPA.PRO registry
Medozon ozone therapy device with accessories: Hyper Medozon Comfort ozone therapy device
Medical device, Roszdravnadzor registration certificate / CE
In the registry →

Architectural integration and treatment rooms

Resort rooms housing the treatment station (with SanPiN norms and MEP loads)

All treatment rooms →
1.3.1 120.0 m² · Class B

Treatment room for intravenous infusions / treatment room / laser blood irradiation / ozone therapy room / blood UV irradiation (10 individual cubicles)

General therapeutic interventions and high-tech therapy · Equipment: 11 538 900 ₽

Treatment room passport →

Unit economics and resort price benchmarks

Market analysis based on a sample of premium sanatoriums, wellness hotels and preventive medicine clinics

Market price corridor
25th percentile (P25) 1 725 ₽
Market median 2 050 ₽
75th percentile (P75) 2 375 ₽

Median of prices in industry facilities' price lists, 2026

Basis of the price benchmark

Prices for this procedure appear in the price lists of 2 industry facilities; the median and interquartile range across facilities are shown (each facility counts once).

Evidence base

Few studies have been published on minor autohaemotherapy with ozone; for autologous blood injection there are reviews of small studies with mixed conclusions.

Publication level D · Scarce data
  1. 1.
    Intramuscular autologous blood therapy - a systematic review of controlled trials.
    BMC Complement Altern Med, 2019 · Systematic review of controlled studies · PMID 31488127
    There is some evidence of effect in urticaria and atopic eczema; RCTs are needed for firm conclusions.
  2. 2.
    Efficacy of autologous whole blood or serum therapy for chronic spontaneous urticaria: a systematic review and meta-analysis.
    J Dermatolog Treat, 2019 · Systematic review and meta-analysis · PMID 30661442
    Chronic urticaria: differences from placebo not significant; no serious adverse events.
  3. 3.
    [Efficacy and safety of autohemotherapy at acupoint for acne: systematic review].
    Zhongguo Zhen Jiu, 2018 · Systematic review · PMID 30672247
    Acne: autohaemotherapy into acupuncture points is more effective than control treatment.
  4. 4.
    A systematic review and meta-analysis of acupoint autohemotherapy and western medicine therapy in treating chronic obstructive pulmonary disease.
    Complement Ther Clin Pract, 2021 · Systematic review and meta-analysis · PMID 33756218
    COPD: autohaemotherapy into points combined with drugs is better than drugs alone, but RCTs are few and of low quality.

Publications were found in PubMed; titles and journals are given verbatim, conclusions are a brief summary of the abstracts under the conditions of the specific studies. The level shows the volume of published data, not the value of the method: A — Plenty of data: consistent systematic reviews and meta-analyses of RCTs; B — Some data: reviews or several RCTs, results are heterogeneous; C — Little data: single RCTs or controlled studies; D — Scarce data: mainly reviews, observational and experimental studies. The passport is updated as new work is published and with regard to international practice.