MEDISPA.PRO
Ministry of Health code: A20.30.026 Axis M3 · Mitochondrial health and energy metabolism CEBM: Level B (High-tech oxygen therapy)

Normobaric oxygen therapy (oxygen chamber, oxygen inhalation)

Normobaric Oxygen Therapy

Industry clinical and economic procedure passport. Full biological mechanism (MoA), patient preparation protocol, first-choice equipment fleet, integration into the resort's master treatment rooms and market price benchmarks.

To the procedure catalogue Equipment fleet Integration treatment rooms Rates and economics
Session duration
30 min
Turnover: ~45 min
Recommended course
10 sessions
10 treatments – an assumption for the economic calculation; the course is prescribed by a physician
Throughput capacity
11 pts
per 8-hour shift
Median rate
1 850 ₽
1 300 ₽ – 3 115 ₽
Course cost
18 500 ₽
at market median
Publication volume
Level B
6 publ. in PubMed

Clinical profile

Breathing oxygen at an increased concentration at normal atmospheric pressure. Aborting cluster headache attacks is the best studied use. Studies in myocardial infarction and stroke without hypoxaemia found no benefit, and hyperoxia may reduce cardiac output; wellness oxygen sessions have hardly been studied in clinical research.

Every statement links to a publication in the list below. This is a snapshot of published research, not a final assessment of the method: international practice and integrated protocols often run ahead of official publications. Draft based on published research; requires review by a physician. Revision: 2026-10-17.

Mechanism of action

  • Hyperoxia increases vascular resistance and may reduce cardiac output; there is no evidence that supplemental oxygen increases oxygen delivery to tissues. [5]

Where studies show an effect

  • Cluster headache: inhalation of 100 % oxygen at 6–12 L/min is recommended to abort an attack (level A). [1]
  • Carbon monoxide poisoning: normobaric oxygen is used, but there are fewer neurological sequelae after hyperbaric oxygen therapy. [6]

Open questions and study limitations

  • Myocardial infarction with normal saturation: routine oxygen gives no clinical benefit; harm is not ruled out. [2, 3]
  • Acute stroke: a 2022 meta-analysis found no effect on early recovery, functional outcome or mortality. [4]

Safety

  • Patients with heart failure are the most sensitive to the haemodynamic effects of hyperoxia. [5]
Contraindications. Contraindications are determined by the physician according to the equipment or drug instructions; they are not given in study abstracts.

Equipment fleet and fit-out

Certified first-choice medical equipment and compatible device systems

Equipment registry
Base configuration (Hero Device)
Oxygen concentrator / normobaric oxygen chamber

Device platform with proven validation of the biological response. Includes built-in biofeedback sensor systems, patient protection protocols and precision dosing of exposure.

Certification: Russian Ministry of Health registration certificate / CE Medical Device Directive Class IIa/IIb.
Compatible platforms in the MEDISPA.PRO registry
Oxygen concentrator
Medical device, Roszdravnadzor registration certificate / CE
In the registry →
normobaric oxygen chamber
Medical device, Roszdravnadzor registration certificate / CE
In the registry →

Architectural integration and treatment rooms

Resort rooms housing the treatment station (with SanPiN norms and MEP loads)

All treatment rooms →
1.3.5 30.0 m² · Class B

Gas inhalation therapy room

General therapeutic interventions and high-tech therapy · Equipment: 11 976 600 ₽

Treatment room passport →

Unit economics and resort price benchmarks

Market analysis based on a sample of premium sanatoriums, wellness hotels and preventive medicine clinics

Market price corridor
25th percentile (P25) 1 300 ₽
Market median 1 850 ₽
75th percentile (P75) 3 115 ₽

Median of prices in industry facilities' price lists, 2026

Basis of the price benchmark

Prices for this procedure appear in the price lists of 3 industry facilities; the median and interquartile range across facilities are shown (each facility counts once).

Evidence base

There is a level A recommendation for aborting cluster headache; in myocardial infarction and stroke without hypoxaemia, meta-analyses found no benefit.

Publication level B · Some data
  1. 1.
    Acute and preventive pharmacologic treatment of cluster headache.
    Neurology, 2010 · Systematic review and guideline · PMID 20679639
    Cluster headache: 100 % oxygen at 6–12 L/min is level A for aborting an attack.
  2. 2.
    Oxygen therapy for acute myocardial infarction.
    Cochrane Database Syst Rev, 2016 · Cochrane systematic review · PMID 27991651
    Myocardial infarction: RCTs showed no benefit of routine oxygen; harm cannot be ruled out.
  3. 3.
    Effects of supplemental oxygen therapy in patients with suspected acute myocardial infarction: a meta-analysis of randomised clinical trials.
    Heart, 2018 · Meta-analysis of RCTs · PMID 29599378
    Suspected myocardial infarction without hypoxaemia: oxygen gives no significant clinical benefit.
  4. 4.
    Normobaric Oxygen Therapy in Acute Stroke: A Systematic Review and Meta-Analysis.
    Cerebrovasc Dis, 2022 · Systematic review and meta-analysis · PMID 34983045
    Acute stroke: the meta-analysis found no effect on recovery, outcome or mortality.
  5. 5.
    Hemodynamic effects of acute hyperoxia: systematic review and meta-analysis.
    Crit Care, 2018 · Systematic review and meta-analysis · PMID 29477145
    Hyperoxia reduces cardiac output and increases vascular resistance; an increase in oxygen delivery was not shown in the analysis.
  6. 6.
    Treatment with normobaric or hyperbaric oxygen and its effect on neuropsychometric dysfunction after carbon monoxide poisoning: A systematic review and meta-analysis of randomized controlled trials.
    Medicine (Baltimore), 2018 · Systematic review and meta-analysis · PMID 30278526
    Carbon monoxide poisoning: fewer neurological sequelae after a hyperbaric chamber than after normobaric oxygen.

Publications were found in PubMed; titles and journals are given verbatim, conclusions are a brief summary of the abstracts under the conditions of the specific studies. The level shows the volume of published data, not the value of the method: A — Plenty of data: consistent systematic reviews and meta-analyses of RCTs; B — Some data: reviews or several RCTs, results are heterogeneous; C — Little data: single RCTs or controlled studies; D — Scarce data: mainly reviews, observational and experimental studies. The passport is updated as new work is published and with regard to international practice.