MEDISPA.PRO
Ministry of Health code: A11.01.003 Axis M4 · Musculoskeletal system and kinesiotherapy CEBM: Level B (Injection methods)

Platelet-rich plasma injections (PRP, plasmolifting)

Platelet-Rich Plasma (PRP) Injections

Industry clinical and economic procedure passport. Full biological mechanism (MoA), patient preparation protocol, first-choice equipment fleet, integration into the resort's master treatment rooms and market price benchmarks.

To the procedure catalogue Equipment fleet Integration treatment rooms Rates and economics
Session duration
40 min
Turnover: ~55 min
Recommended course
3 sessions
3 treatments – an assumption for the economic calculation; the course is prescribed by a physician
Throughput capacity
9 pts
per 8-hour shift
Median rate
9 200 ₽
8 162 ₽ – 23 325 ₽
Course cost
27 600 ₽
at market median
Publication volume
Level B
6 publ. in PubMed

Clinical profile

Injection of a platelet concentrate from the patient's own blood into a joint, tendon or skin. Meta-analyses show clinically significant improvement in knee osteoarthritis (better than placebo and hyaluronic acid) and in plantar fasciitis; for tendinopathies and alopecia the evidence is of low quality.

Every statement links to a publication in the list below. This is a snapshot of published research, not a final assessment of the method: international practice and integrated protocols often run ahead of official publications. Draft based on published research; requires review by a physician. Revision: 2026-10-17.

Where studies show an effect

  • Knee osteoarthritis: clinically significant improvement in function up to 12 months and pain reduction at 3–6 months versus placebo. [1]
  • In knee osteoarthritis, PRP gives better results than hyaluronic acid. [2]
  • Plantar fasciitis: greater pain reduction than after corticosteroids, shockwave therapy and placebo. [3]
  • Lateral epicondylitis: injection therapy with autologous blood and PRP is effective. [6]

Open questions and study limitations

  • Tendinopathies: effect comparable to other ultrasound-guided injections; evidence of low and very low quality. [4]
  • Alopecia: evidence of benefit is limited and mostly of low quality. [5]
  • In plantar fasciitis, the advantage does not hold for all outcome measures. [3]

Safety

  • Injection-site pain is more common than after other ultrasound-guided injections. [4]

Protocol in studies

  • In knee osteoarthritis, the effect depends on platelet concentration. [1]
  • Leucocyte-poor PRP may be preferable in knee osteoarthritis. [2]
Contraindications. Contraindications are determined by the physician according to the equipment or drug instructions; they are not given in study abstracts.

Equipment fleet and fit-out

Certified first-choice medical equipment and compatible device systems

Equipment registry
Base configuration (Hero Device)
Laboratory centrifuge, PRP tubes

Device platform with proven validation of the biological response. Includes built-in biofeedback sensor systems, patient protection protocols and precision dosing of exposure.

Certification: Russian Ministry of Health registration certificate / CE Medical Device Directive Class IIa/IIb.
Compatible platforms in the MEDISPA.PRO registry
Laboratory centrifuge
Medical device, Roszdravnadzor registration certificate / CE
In the registry →
PRP tubes
Medical device, Roszdravnadzor registration certificate / CE
In the registry →

Architectural integration and treatment rooms

Resort rooms housing the treatment station (with SanPiN norms and MEP loads)

All treatment rooms →
1.1.3 30.0 m² · Class V

Orthopaedic trauma surgeon's room with treatment room

Physicians' consulting and examination rooms · Equipment: 5 681 450 ₽

Treatment room passport →
2.4.1 25.0 m² · Class B

Cosmetologist's treatment room

Cosmetology, aesthetic medicine and body aesthetics · Equipment: 37 259 600 ₽

Treatment room passport →

Unit economics and resort price benchmarks

Market analysis based on a sample of premium sanatoriums, wellness hotels and preventive medicine clinics

Market price corridor
25th percentile (P25) 8 162 ₽
Market median 9 200 ₽
75th percentile (P75) 23 325 ₽

Median of prices in industry facilities' price lists, 2026

Basis of the price benchmark

Prices for this procedure appear in the price lists of 6 industry facilities; the median and interquartile range across facilities are shown (each facility counts once).

Evidence base

Meta-analyses of RCTs show benefit in knee osteoarthritis and plantar fasciitis; for other indications the evidence is of low quality.

Publication level B · Some data
  1. 1.
    PRP Injections for the Treatment of Knee Osteoarthritis: The Improvement Is Clinically Significant and Influenced by Platelet Concentration: A Meta-analysis of Randomized Controlled Trials.
    Am J Sports Med, 2025 · Meta-analysis · PMID 39751394
    Knee osteoarthritis: clinically significant improvement in function up to 12 months and in pain at 3–6 months versus placebo; platelet concentration matters.
  2. 2.
    Platelet-Rich Plasma Versus Hyaluronic Acid for Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
    Am J Sports Med, 2021 · Systematic review and meta-analysis of RCTs · PMID 32302218
    Knee osteoarthritis: results better than after hyaluronic acid; leucocyte-poor PRP may be preferable.
  3. 3.
    Platelet rich plasma therapy versus other modalities for treatment of plantar fasciitis: A systematic review and meta-analysis.
    Foot Ankle Surg, 2024 · Systematic review and meta-analysis · PMID 38395675
    Plantar fasciitis: less pain than after corticosteroids, ESWT and placebo; the advantage does not hold for all outcomes.
  4. 4.
    Ultrasound-guided injection of platelet-rich plasma for tendinopathies: a systematic review and meta-analysis.
    Blood Transfus, 2023 · Systematic review and meta-analysis · PMID 36346880
    Tendinopathies: effect comparable to other injections, low-quality evidence; injection-site pain is more common.
  5. 5.
    Platelet-rich plasma for the treatment of alopecia: a systematic review and meta-analysis.
    Blood Transfus, 2023 · Systematic review and meta-analysis · PMID 34967722
    Alopecia: evidence of benefit is limited and mostly of low quality.
  6. 6.
    Treatment Options for Tennis Elbow - An Umbrella Review.
    Folia Med Cracov, 2023 · Umbrella review · PMID 38310528
    Lateral epicondylitis: autologous blood and PRP injections are effective.

Publications were found in PubMed; titles and journals are given verbatim, conclusions are a brief summary of the abstracts under the conditions of the specific studies. The level shows the volume of published data, not the value of the method: A — Plenty of data: consistent systematic reviews and meta-analyses of RCTs; B — Some data: reviews or several RCTs, results are heterogeneous; C — Little data: single RCTs or controlled studies; D — Scarce data: mainly reviews, observational and experimental studies. The passport is updated as new work is published and with regard to international practice.