MEDISPA.PRO
Ministry of Health code: A12.09.002.003 Axis M0 · Introductory check-up and longevity biomarkers CEBM: Level A (Functional diagnostics and check-up)

Cardiopulmonary exercise testing (CPET spiroergometry / VO2max)

Cardiopulmonary Exercise Testing (CPET / VO2max)

Industry clinical and economic procedure passport. Full biological mechanism (MoA), patient preparation protocol, first-choice equipment fleet, integration into the resort's master treatment rooms and market price benchmarks.

Session duration
60 min
Turnover: ~75 min
Recommended course
1 sessions
once every 6 months (dynamic monitoring of exercise tolerance)
Throughput capacity
6 pts
per 8-hour shift
Median rate
2 250 ₽
1 588 ₽ – 3 400 ₽
Course cost
2 250 ₽
at market median
Publication volume
Level A
8 publ. in PubMed

Clinical profile

Exercise test on a cycle ergometer or treadmill with expired gas analysis: measures peak oxygen uptake (VO₂peak), anaerobic threshold and ventilatory efficiency. The method is standardised by international guidelines; the cardiorespiratory fitness it measures is one of the strongest predictors of mortality and chronic disease.

Every statement links to a publication in the list below. This is a snapshot of published research, not a final assessment of the method: international practice and integrated protocols often run ahead of official publications. Draft based on published research; requires review by a physician. Revision: 2026-10-17.

Mechanism of action

  • The test assesses the combined work of the heart, lungs and muscles under increasing load; its interpretation is described in scientific statements of cardiology societies. [4, 5]

Where studies show an effect

  • Assessment of cardiorespiratory fitness as a prognostic factor: high fitness is consistently associated with lower risk of death and chronic disease (review of meta-analyses, more than 20.9 million observations). [1]
  • People with a maximal aerobic capacity of 7.9 METs or higher have markedly lower mortality and incidence of CHD and CVD. [2]
  • Chronic lung disease: standardised use for diagnosis and assessment of exercise limitation. [6, 3]
  • Preoperative risk stratification and prognosis in specific heart diseases. [7, 8]

Open questions and study limitations

  • Large prospective studies are needed for preoperative assessment and prognosis in amyloid cardiomyopathy. [7, 8]

Safety

  • Test performance and interpretation are standardised in the ATS/ACCP and American Heart Association guidelines. [3, 4]

Protocol in studies

  • ERS standard: at least 3 minutes at rest, 3 minutes of unloaded exercise, 8–12 minutes of linearly increasing load (increments at least once a minute), then recovery of at least 2–3 minutes. [6]
Contraindications. Contraindications to exercise testing are determined by the functional diagnostics physician according to ATS/ACCP and AHA guidelines.

Equipment fleet and fit-out

Certified first-choice medical equipment and compatible device systems

Equipment registry
Base configuration (Hero Device)
Cortex MetaLyzer 3B / Cosmed Quark CPET cardiopulmonary exercise gas analysis system

Device platform with proven validation of the biological response. Includes built-in biofeedback sensor systems, patient protection protocols and precision dosing of exposure.

Certification: Russian Ministry of Health registration certificate / CE Medical Device Directive Class IIa/IIb.
Compatible platforms in the MEDISPA.PRO registry
Skillrun professional treadmill with adaptive cushioning
Medical device, Roszdravnadzor registration certificate / CE
In the registry →
Treadmill test (GE T-2100 or Schiller MTM 1500)
Medical device, Roszdravnadzor registration certificate / CE
In the registry →
Recline horizontal medical cycle ergometer with ECG monitoring
Medical device, Roszdravnadzor registration certificate / CE
In the registry →

Architectural integration and treatment rooms

Resort rooms housing the treatment station (with SanPiN norms and MEP loads)

All treatment rooms →

Unit economics and resort price benchmarks

Market analysis based on a sample of premium sanatoriums, wellness hotels and preventive medicine clinics

Market price corridor
25th percentile (P25) 1 588 ₽
Market median 2 250 ₽
75th percentile (P75) 3 400 ₽

Median of prices in industry facilities' price lists, 2026

Basis of the price benchmark

Prices for this procedure appear in the price lists of 4 industry facilities; the median and interquartile range across facilities are shown (each facility counts once).

Evidence base

The method is standardised by international guidelines; the prognostic value of the measured fitness is confirmed by meta-analyses of millions of observations.

Publication level A · Plenty of data
  1. 1.
    Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among adults: an overview of meta-analyses representing over 20.9 million observations from 199 unique cohort studies.
    Br J Sports Med, 2024 · Review of meta-analyses · PMID 38599681
    High cardiorespiratory fitness is consistently associated with lower risk of death and chronic disease.
  2. 2.
    Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis.
    JAMA, 2009 · Meta-analysis · PMID 19454641
    Better fitness means lower risk of death and CHD/CVD; the threshold is about 7.9 METs.
  3. 3.
    ATS/ACCP Statement on cardiopulmonary exercise testing.
    Am J Respir Crit Care Med, 2003 · ATS/ACCP guidelines · PMID 12524257
    International standard for performing and interpreting the cardiopulmonary exercise test.
  4. 4.
    Clinician's Guide to cardiopulmonary exercise testing in adults: a scientific statement from the American Heart Association.
    Circulation, 2010 · AHA scientific statement · PMID 20585013
    A clinician's guide to cardiopulmonary exercise testing in adults.
  5. 5.
    EACPR/AHA Scientific Statement. Clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations.
    Circulation, 2012 · EACPR/AHA scientific statement · PMID 22952317
    Recommendations on interpreting test data in specific patient groups.
  6. 6.
    ERS statement on standardisation of cardiopulmonary exercise testing in chronic lung diseases.
    Eur Respir Rev, 2019 · ERS statement · PMID 31852745
    Standardisation of the test protocol in chronic lung disease.
  7. 7.
    Cardiopulmonary exercise testing prior to radical cystectomy: a systematic review and meta-analysis.
    BJU Int, 2024 · Systematic review and meta-analysis · PMID 39258430
    Before radical cystectomy, poorer test results are associated with higher 90-day mortality.
  8. 8.
    Cardiopulmonary exercise testing predicts prognosis in amyloid cardiomyopathy: a systematic review and meta-analysis.
    ESC Heart Fail, 2023 · Systematic review and meta-analysis · PMID 37264762
    In amyloid cardiomyopathy, the test helps identify patients at increased risk of death.

Publications were found in PubMed; titles and journals are given verbatim, conclusions are a brief summary of the abstracts under the conditions of the specific studies. The level shows the volume of published data, not the value of the method: A — Plenty of data: consistent systematic reviews and meta-analyses of RCTs; B — Some data: reviews or several RCTs, results are heterogeneous; C — Little data: single RCTs or controlled studies; D — Scarce data: mainly reviews, observational and experimental studies. The passport is updated as new work is published and with regard to international practice.